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Allergic Response to Pollen

Allergic Response to Pollen

 

Allergic Response to Pollen
Image Number: 139-038
Dimensions: 8.5 x 11
Media Used: Airbrush Acrylic
Formats Available: Transparency
Title: Allergic Response to Pollen
Customization: Available
Image Description:  Allergic response causes release of histamine by mast cells triggered by the crosslinking of protein from pollen grains in the nasal passage.

© Mark Lefkowitz, Biomedical Vis
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Allergic Response to Pollen


  View Image #139-038 Allergic Response to Pollen #139-038  
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Allergic response causes release of histamine by mast cells triggered by the crosslinking of protein from pollen grains in the nasal passage.


  View Image #111-187 Allergic Response #111-187  
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Cellular events tell the story of extreme allergic response (anaphylactic shock) to an allergen such as pollen. Commercial requests only. Minimum license fee is $300. No student or classroom requests will be answered. Copyright Teri J. McDermott


  View Image #118-076 Allergy, Hypersensitivity Anaphylactic Response #118-076  
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Allergic Hypersensitivity Response, Anaphylaxic Response. An allergy is an abnormal, acquired sensitivity to a given substance, including pollen, drugs, or numerous environmental triggers. Type I hypersensitivity is characterized by excessive activation of mast cells and basophils by IgE, resulting in a systemic inflammatory response that can result in symptoms as benign as a runny nose, to life-threatening anaphylactic shock and death. Type 1 hypersensitivity is an allergic reaction provoked by reexposure to a specific type of antigen referred to as an allergen. Exposure may be by ingestion, inhalation, injection, or direct contact. The difference between a normal immune response and a type I hypersensitive response is that plasma cells secrete IgE. This class of antibodies binds to Fc receptors on the surface of tissue mast cells and blood basophils. Mast cells and basophils coated by IgE are "sensitized." Later exposure to the same allergen, cross-links the bound IgE on sensitized cells resulting in degranulation and the secretion of pharmacologically active mediators such as histamine, leukotriene, and prostaglandin that act on the surrounding tissues. The principal effects of these products are vasodilation and smooth-muscle contraction. The reaction may be either local or systemic. Symptoms vary from mild irritation to sudden death from anaphylactic shock. Treatment usually involves epinephrine, antihistamines, and corticosteroids.


  View Image #118-115 Allergic Reaction, Hypersensitivity #118-115  
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Allergic Reaction. Type 1 hypersensitivity is an allergic reaction provoked by reexposure to a specific type of antigen referred to as an allergen.[3] Exposure may be by ingestion, inhalation, injection, or direct contact. The difference between a normal immune response and a type I hypersensitive response is that plasma cells secrete IgE. This class of antibodies binds to Fc receptors on the surface of tissue mast cells and blood basophils. Mast cells and basophils coated by IgE are "sensitized." Later exposure to the same allergen, cross-links the bound IgE on sensitized cells resulting in degranulation and the secretion of pharmacologically active mediators such as [[mastcell ]], leukotriene, and prostaglandin that act on the surrounding tissues. The principal effects of these products are vasodilation and smooth-muscle contraction. The reaction may be either local or systemic. Symptoms vary from mild irritation to sudden death from anaphylactic shock. Treatment usually involves epinephrine, antihistamines, and corticosteroids. If the entire body gets involved, then anaphylaxis can take place; an acute, systemic reaction that can prove fatal.


  View Image #118-077 Allergy, Hypersensitivity Anaphylactic Response #118-077  
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Allergy, Anaphylactic Response. Allergy, Hypersensitivity Anaphylactic Responsecharacterized by excessive activation of mast cells and basophils by IgE, resulting in a systemic inflammatory response that can result in symptoms as benign as a runny nose, to life-threatening anaphylactic shock and death. Type 1 hypersensitivity is an allergic reaction provoked by reexposure to a specific type of antigen referred to as an allergen. Exposure may be by ingestion, inhalation, injection, or direct contact. The difference between a normal immune response and a type I hypersensitive response is that plasma cells secrete IgE. This class of antibodies binds to Fc receptors on the surface of tissue mast cells and blood basophils. Mast cells and basophils coated by IgE are "sensitized." Later exposure to the same allergen, cross-links the bound IgE on sensitized cells resulting in degranulation and the secretion of pharmacologically active mediators such as histamine, leukotriene, and prostaglandin that act on the surrounding tissues. The principal effects of these products are vasodilation and smooth-muscle contraction. The reaction may be either local or systemic. Symptoms vary from mild irritation to sudden death from anaphylactic shock. Treatment usually involves epinephrine, antihistamines, and corticosteroids.

 
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